Vacancies and Studentships.

We have a potential studentship working in the IGF2R domain 11 research project that would be aimed at engineering domain 11 for specific ligand binding. Recently we have used NMR, X-ray crystallography and yeast surface display assays to engineer an Insulin growth factor 2 (IGF2) super-antagonist based on domain 11 from the IGF2 receptor (IGF2R) (Crump & Hassan and co-workers 2012, Science 238, 1209-1213.) and the proposed PhD will build on this success by adapting domain 11 to a wider range of ligands. This studentship would be funded by the SWSBIO DTP (BBSRC) and would start for four years in October 2015.  Please contact for further details or see Please note there will be an interview process for these studentships and final selection for a PhD will be based on this performance.

Supervisors: Prof. Matthew Crump (School of Chemistry, University of Bristol), Paul Race (School of Biochemistry, University of Bristol), Bass Hassan (Sir William Dunn School of Medicine, University of Oxford).