The Crump group is pleased to announce the publication of recent work in ACS Chemical Biology Journal. This work was completed as a collaboration between the Departments of Chemistry and Biochemistry at the University of Bristol, showing the need for frequent collaboration in the field of biosynthesis of natural products.
This work utilises a plethora of laboratory techniques to fully characterise the formation of a 3-carbon alcohol intermediate in the biosynthesis of the polyketide antibiotic mupirocin and homologous 4-carbon alcohol intermediate in the biosynthesis of thiomarinol.
This is exciting work and provides a solid contribution to the biosynthetic community, well done to all involed in the publication of this work.
A link to the paper can be found at the following link: https://doi.org/10.1021/acschembio.9b00969